Side effects of sumatriptan (oral administration). (2023)

Brand description and names

Drug information provided by:IBM Micromedex

american brand

1. imiterx

Descriptions

Sumatriptan is used to treat acute migraines in adults. It is not used to prevent migraines and is not used for cluster headaches. Sumatriptan works in the brain to relieve migraine pain. It belongs to a group of medicines called triptans.

Many people find that their headaches go away completely after taking sumatriptan. Other people find that their headaches are much less painful and that they can return to their normal activities, even if their headaches are not completely gone. Sumatriptan often relieves other symptoms that occur along with a migraine, such as nausea, vomiting, sensitivity to light, and sensitivity to sound.

Sumatriptan is not a common pain reliever. It will not relieve pain other than migraines. This medicine is usually used for people whose headaches are not relieved by acetaminophen, aspirin or other pain relievers.

Sumatriptan has caused serious side effects in some people, especially those with heart or blood vessel disease. Be sure to discuss with your doctor the risks of using this medication, as well as any benefits it may have.

This medicine is only available with a prescription.

This product is available in the following dosage forms:

• Board

Before using

When deciding to use a medication, the risks of taking it must be weighed against the good it will do. This is a decision for you and your doctor to make. For this drug, the following should be considered:

allergies

Tell your doctor if you have ever had an allergic or unusual reaction to this medicine or any other medicine. Also tell your healthcare professional if you have any other allergies, such as food, dyes, preservatives or animals. For over-the-counter products, read the label or packaging ingredients carefully.

Pediatric

Appropriate studies on the relationship of age to the effects of sumatriptan in the pediatric population have not been performed. Safety and efficacy have not been established.

geriatric

Sumatriptan is not recommended for use in elderly patients with kidney problems, heart or blood vessel disease, or high blood pressure, and should not be used in elderly patients with liver problems.

Breast-feeding

There are no adequate studies in women to determine the infant risk of using this medication while breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug interactions

While certain drugs should not be used together, in other cases, two different drugs can be used together even if an interaction occurs. In these cases your doctor may want to change the dose or other precautions may be necessary. When you are taking this medication, it is especially important that your healthcare professional knows if you are taking any of the medications listed below. The following interactions have been selected based on their potential importance and are not necessarily exhaustive.

The use of this medication with any of the following medications is not recommended. Your doctor may decide not to treat you with this medicine or change some of the other medicines you are taking.

• almotriptano
• bromocriptine
• dihydroergotamine
• electricity
• Mesilatos ergoloides
• Ergonovina
• Ergotamine
• frovatriptan
• furazolidona
• Iproniazid
• isocarboxazid
• linezolid
• Methylene blue
• Methylergonovina
• metisergida
• moclobemida
• naratriptán
• nialamide
• fennel
• procarbazina
• rasagilina
• Rizatriptan
• Safinamida
• selegilina
• tranylcypromine
• Zolmitriptan

Using this medication with any of the following medications is generally not recommended, but may be necessary in some cases. If both drugs are prescribed together, your doctor may change the dose or how often you use one or both drugs.

• alfentanilo
• Amineptin
• amitriptyline
• amitriptyline oxide
• amoxapine
• Amphetamine
• Benzhidrocodona
• Benzfetamina
• buprenorphine
• bupropion
• butorfanol
• citalopram
• clomipramina
• Codeine
• desipramin
• desvenlafaxine
• dexfenfluramina
• dextroanfetamina
• dextrometorfano
• despised
• dihydrocodeine
• dolasetron
• doxepina
• Duloxetine
• escitalopram
• Fenfluramina
• fentanyl
• fluoxetine
• fluvoxamina
• granissetron
• hydrocodone
• hydromorphone
• imipramine
• lasmiditano
• levomilnacipran
• levorfanol
• lisdexanfetamina
• Lithium
• lofepramina
• for Lorcaser
• melitraceno
• meperidina
• metaxalone
• methamphetamine
• milnacipran
• mirtazapine
• Morphine
• Morphine Sulfate Liposome
• nalbuphine
• Nephasodonta
• nortriptilina
• ondansetron
• opipramol
• oxicodona
• oxymorphone
• palonosetron
• paroxetine
• pentazocine
• protriptilina
• reboxetine
• remifentanil
• sertraline
• sibutramine
• st john's grass
• sufentanilo
• Tapentadol
• tianeptine
• tramadol
• trazodone
• trimipramine
• venlafaxine
• Vilazodona
• vortioxetine
• Ziprasidone

Other interactions

Certain medications should not be used at or near the time of eating food or certain types of food, as interactions may occur. The use of alcohol or tobacco with certain medications can also cause interactions. Talk to your healthcare professional about using medications with food, alcohol, or tobacco.

Other medical problems

The presence of other medical problems may affect the use of this medication. Be sure to let your doctor know if you have any other medical issues, especially:

• Angina (chest pain) or
• Arrhythmia (heart rhythm problem) or
• Basilar migraine (migraine with vision and hearing problems) or
• Cerebrovascular disease (eg, stroke, transient ischemic attack) or history or
• Heart attack, history of the
• Heart or blood vessel problems or
• Hemiplegic migraine (migraine with some paralysis) or
• Hypertension (high blood pressure), uncontrolled or
• Ischemic bowel disease (the intestines have little blood supply) or
• Severe liver disease or
• peripheral vascular disease (clogged arteries) or
• Cerebrovascular accident, history of
• Transient ischemic attack (TIA), history or
• Wolff-Parkinson-White syndrome (heart rhythm problem): Should not be used in patients with these conditions.

• Seizures or epilepsy, history of or
• Stomach or intestinal bleeding – use with caution. It can make these conditions worse.

• Coronary artery disease, history or
• Diabetes o
• Hypercholesterolemia (high blood cholesterol) or
• Hypertension (high blood pressure), controlled or
• Mild to moderate liver disease or
• obesity or
• Raynaud's Syndrome – Use with caution. You may be at greater risk for more serious side effects.

proper use

Do not use this medication for headaches other than your usual migraines. Talk to your doctor about what to do for regular headaches.

To relieve your migraine as quickly as possible, use this medication as soon as the headache starts. Even if you get warning signs of an upcoming migraine (an aura), you should wait until the headache starts before using sumatriptan.

Ask your doctor ahead of time about any other medications you can take if sumatriptan doesn't work. After using the other medicine, consult your doctor as soon as possible. Headaches that are not relieved by sumatriptan are sometimes caused by conditions that require other treatment.

If you feel much better after a dose of sumatriptan, but your headache comes back or gets worse after a while, wait at least 2 hours before taking another dose. However, use this medication only as directed by your doctor. Do not use more and do not use more often than recommended. Using too much sumatriptan can increase the chance of side effects. Do not take more than 200 mg in 24 hours.

Swallow the tablet whole with water or other liquids. Do not tear, break or chew.

You can take the tablet with or without food.

This medicine comes with the leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

dosage

The dose of this medicine will be different for different patients. Follow your doctor's instructions or the instructions on the label. The following information only includes the average doses of this medication. If your dose is different, do not change it unless your doctor tells you to.

The amount of medicine you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medication depend on the medical condition you are using the medication for.

• For the oral pharmaceutical form (tablets):
  • For migraines:
    • Adults: 25, 50, or 100 milligrams (mg) in a single dose. If you feel any relief, or if the migraine comes back after it has disappeared, you can take another dose 2 hours after the last dose. Do not take more than 200mg in any 24 hour period.
    • Children: the doctor must determine the use and dosage.

Store

Store the medicine in a closed container at room temperature, away from heat, moisture and direct light. Prevent it from freezing.

Keep out of the reach of children.

Do not store expired or no longer needed medications.

Ask your healthcare professional how to dispose of any unused medicine.

Precautions

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and decide if you should continue to use it.

Check with your doctor if you used this medication and it didn't work. Also, check with your doctor if your migraines get worse or occur more frequently since you started using this medication.

You should not use this medication if you have used an MAOI inhibitor (MAOI) such as phenelzine (Nardil®) or tranylcypromine (Parnate®) in the last 2 weeks. Do not use this medication if you have taken other triptan migraine medications or ergot-type medications in the past 24 hours. Some examples of triptan medications are almotriptan (Axert®), eletriptan (Relpax®), naratriptan (Amerge®), or zolmitriptan (Zomig®). Some examples of ergot-type medications are dihydroergotamine (D.H.E. 45®, Migranal®), ergotamine (Bellergal®, Cafergot®, Ergomar®, Wigraine®) or methysergide (Sansert®).

This medication can cause problems if you have heart disease. If your doctor thinks you may have a problem with this medication, he may want you to have your first dose in the office or clinic.

This medication may increase your risk of having an abnormal heart rhythm, heart attack, angina, or stroke. This is more likely to happen if you or a family member already has heart disease, if you have diabetes, high blood pressure, high cholesterol, or if you smoke. Call your doctor right away if you have any symptoms of a heart problem, such as chest pain or discomfort, irregular heartbeat, nausea or vomiting, pain or discomfort in your shoulders, arms, jaw, back, or neck, trouble breathing, or sweating. Call your doctor right away if you have any symptoms of a stroke, such as confusion, slurred speech, double vision, headaches, inability to move your arms, legs, or facial muscles, inability to speak, or slow speech.

Consult your doctor immediately if you experience chest discomfort, jaw tightness, or neck tightness after using this medication. Also, tell your doctor if you have sudden or severe abdominal or stomach pain or bloody diarrhea after using this medication.

See your doctor immediately if you experience blurred vision, difficulty reading, or any other changes in vision during or after treatment. An ophthalmologist (ophthalmologist) may need to check your eyes.

Using sumatriptan alone or in combination with other migraine medications for 10 or more days a month may make your headache worse. You can keep a headache diary to record the frequency of your headaches and drug use.

Be sure to tell your doctor about all other medications you are using. Sumatriptan can cause a serious condition called serotonin syndrome when taken with some medications. This especially includes medications used to treat depression such as citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine, Celexa®, Cymbalta®, Effexor®, Lexapro®, Luvox®, Paxil®, Prozac®, Sarafem® , Symbyax® or Zoloft®. See your doctor immediately if you experience agitation, confusion, diarrhea, abnormal excited speech, fever, overactive reflexes, incoordination, restlessness, chills, sweating, tremors or tremors you can't control, or spasms. These could be symptoms of serotonin syndrome.

This medication can cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis requires immediate medical attention. The most serious signs of this reaction are very rapid or irregular breathing, shortness of breath, wheezing, or fainting. Other signs may include changes in facial skin color, a very fast but irregular heartbeat or pulse, hive-like bumps on the skin, and puffiness or puffiness of the eyelids or around the eyes. If these effects occur, seek emergency help immediately.

Drinking alcohol can make headaches worse or cause new headaches. People suffering from severe headaches should probably avoid alcoholic beverages, especially during a headache.

Some people feel dizzy or drowsy during or after a migraine, or use sumatriptan for migraine relief. While you feel dizzy or drowsy, do not drive, use machinery or do anything that could be dangerous if you are dizzy or not alert.

Secundary effects

Along with its necessary effects, a drug can cause some unwanted effects. While not all of these side effects may occur, if they do, they may require medical attention.

Talk to your doctor right away if you experience any of the following side effects:

less common

1. Abdominal or stomach pain
2. anxiety
3. blurred vision
4. changes in speech patterns and rhythms
5. chest pain or tightness
6. chills
7. confusion
8. dizziness
9. fast, slow, irregular, pulsing, or pounding pulse or heartbeat
10. headache
11. muscle cramps and stiffness
12. neck, throat, or jaw pain
13. Nightmares
14. shivering
15. perspiration
16. swelling of fingers, hands, feet, or legs
17. chest tightness
18. difficulty breathing

Strange

1. Blindness
2. chest pain or discomfort
3. tightness or heaviness in the chest
4. flushing or flushing of the skin, especially on the face and neck
5. increased blinking or twitching of the eyelid
6. itching, pain, redness, or swelling
7. dizziness, lightheadedness, or fainting
8. neuralgia
9. severe numbness, especially on one side of the face or body
10. severe or continuous stomach pain
11. difficulty speaking or swallowing
12. spasms
13. unusual bleeding or bruising
14. vomiting blood or material that looks like coffee grounds
15. weakness of arms and legs

unknown incidence

1. Agitation
2. back, leg, or stomach pain
3. bleeding gums
4. vision changes
5. muscle spasms
6. point out red spots on the skin
7. poor coordination
8. swelling or puffiness of the eyelids or around the eyes, face, lips, or tongue
9. concern
10. rash, hives, or itching
11. unexplained bleeding or bruising
12. exceptionally hot skin
13. weakness in the arm or leg on one side of the body, sudden and severe

There may be some side effects that usually do not require medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your healthcare professional can tell you about ways to prevent or reduce some of these side effects. Check with your healthcare professional if any of the following side effects continue or are bothersome, or if you have any questions about them:

less common

1. Burning sensation, tingling, itching, numbness, tingling, prickling or tingling
2. change in color vision
3. change in hearing
4. hard to focus
5. somnolence
6. acidity
7. increased sensitivity of the eyes to sunlight
8. joint pain
9. muscle pain or cramps
10. muscle stiffness or tension
11. swollen joints
12. trouble sleeping

Strange

1. Aggressiveness
2. belching
3. change of taste
4. feeling halos around the lights
5. increased sensitivity to pain
6. loss of appetite
7. numbness, pain, tingling, or weakness
8. stomach discomfort or pain
9. tingling in hands and feet
10. tunnel vision
11. weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, consult your healthcare professional.

Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: February 1, 2023

Original article:https://www.mayoclinic.org/drugs-supplements/sumatriptan-oral-route/side-effects/drg-20074356

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